Understanding the genetic regulation of plasma inflammatory proteins is essential for bridging the gap between genetics and disease biology. While studies in European populations have highlighted significant genetic influences on inflammatory protein levels, African populations remain underrepresented in immunogenetic...
Caroline Amour, C. Boahen, G. Temba et al.· Genomics, Proteomics & Bioin...· 0 citations
Background: Pseudomonas aeruginosa is a common cause of hospital-acquired infections and is classified as a World Health Organization (WHO) critical-priority pathogen because of its increasing resistance to key antibiotics, including carbapenems. In Tanzania, several studies that documented P. aeruginosa resistance pro...
Miza S. Vuai, Happiness H. Kumburu, Melkiory Beti et al.· East Africa Science· 0 citations
BACKGROUND
Rapid dietary transitions in sub-Saharan Africa may alter coagulation profiles; however, this remains poorly characterized.
METHODS
An open-label dietary-intervention trial in Tanzania enrolled 77 healthy men aged 20 to 40 years. They underwent 1 of 3 interventions (n=22 per arm): heritage-to-Western-style...
Eka Patricia Kisali, M. Roest, T. Pecht et al.· Arteriosclerosis, Thrombosis...· 0 citations
Abstract Background Molecular surveillance is essential to detect emerging artemisinin partial resistance (ART-R) and partner drug resistance in Sub-Saharan Africa. Objectives To describe the prevalence of Plasmodium falciparum resistance markers in two high-burden countries using artesunate-amodiaquine (ASAQ) and arte...
Flory Luzolo Khote, Hypolite Muhindo Mavoko, P. Mitashi et al.· Journal of Antimicrobial Che...· 0 citations
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