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Open access Oct 2026

NRG-BR002: A Randomized Phase II/III Trial of Metastases-Directed Ablation with First-Line Systemic Therapy for Oligometastatic Breast Cancer

Purpose: Metastasis-directed therapy is increasingly used for oligometastatic breast cancer, despite its uncertain benefit during first-line systemic therapy. We evaluated whether metastasis-directed ablation improves progression-free survival (PFS) compared with first-line systemic therapy alone in patients with oligo...

S. Chmura, Kathryn A. Winter, W. Woodward et al. · 0 citations
Open access Sep 2026

Evaluating a shared decision engagement system in the NCI community oncology research program: a multi-level RCT.

BACKGROUND Improving patient-centered care and communication in breast cancer remains challenging in the complex and evolving landscape of breast cancer care delivery. METHODS The SharES (Alliance A231901CD) trial was carried out in collaboration with the NCI Community Oncology Research Program Alliance Research Base...

Sarah T. Hawley, K. Kidwell, R. Jagsi et al. · 0 citations

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