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Author

R. Iggo

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Open access Aug 2026

A functional role for an intronic enhancer of ZBTB16 in AR-mediated tumour suppression in ER+ breast cancer

The androgen receptor (AR) is a tumour suppressor in oestrogen receptor-positive (ER⁺) breast cancer, repressing cell cycle genes and restraining proliferation. We previously identified ZBTB16 as a candidate AR-regulated tumour-suppressor gene. Here, we validated ZBTB16 as a direct AR target and tested whether...

Maliha Wajahat, Dawn G. L. Thean, R. Iggo et al. · 0 citations

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