R. Gordzevich

Electrostatic Modulation of Antibiotic Susceptibility by the Bacterial Donnan Potential

Antibiotic resistance in Gram-negative bacteria is a major global health threat, in part because of the permeability barriers of their double-membrane envelope and active efflux systems. While porins, lipopolysaccharides, and efflux pumps have been extensively studied, the role of membrane energetics, particularly th...