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R. Gijsbers

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Open access Oct 2026

JAK-inhibitor treatment induces rapid yet incomplete immune reconstitution in STAT1 gain-of-function

Iglesias-Herrero et al. longitudinally assess JAK-inhibitor treatment response in two patients with STAT1 gain-of-function and show that it induces rapid but incomplete immune reconstitution, with increased TCR diversity and reversal of monocyte hyperinflammation, highlighting both therapeutic benefit and persistent im...

Cecilia Iglesias-Herrero, W. Roosens, G. Galicia et al. · 0 citations
Open access Aug 2026

Morphological maturation and circuit integration of adult-born neurons are key to functional recovery after traumatic brain injury.

It is revealed that injury-induced adult-born neurons survive, mature, and integrate synaptically into preexisting circuits, and that this coincides with the recovery of learned avoidance behavior by two months postinjury.

Valerie Mariën, Caroline Zandecki, Jolien Van Houcke et al. · 1 citation

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