Author

R. Gacesa

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Open access Sep 2026

A gut microbiome-derived risk score is associated with future cancer development

Cancer remains a leading cause of morbidity and mortality worldwide, and the incidence of new cancer cases is rising. While established lifestyle factors such as smoking, obesity, and diet contribute to cancer risk, the gut microbiome has emerged as a hallmark of cancer. However, the role of the gut microbiome in cance...

E. Oosterhout, R. S. Leijdesdorff, O. Kambur et al. · medRxiv · 0 citations

Open access Oct 2026

Genome-wide analysis of genetic modifiers of Crohn's disease and ulcerative colitis risk in response to tobacco smoking.

BACKGROUND Gene-environment interactions (GxE) are fundamental for understanding the mechanisms of human diseases. Tobacco smoking is of particular interest for Inflammatory bowel disease (IBD), as it worsens Crohn's disease (CD) but protects against ulcerative colitis (UC). Here, we systematically examined the genome-...

Jing-Jing Bai, R. Gacesa, J. Björk et al. · EBioMedicine · 0 citations