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R. G.

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Case report Open access Sep 2026

Van Wyk-Grumbach Syndrome: A Rare Triad of Precocious Puberty, Pituitary Pseudomacroadenoma, and Multicystic Ovaries in an Eight-Year-Old Girl

Van Wyk-Grumbach syndrome (VWGS) is a rare manifestation of chronic, severe primary hypothyroidism in children. It is classically characterized by delayed bone age, short stature, and isosexual precocious puberty, often accompanied by multicystic ovaries and pituitary hyperplasia. Because of its presentation, it is fre...

Prashant T. Bhosale, R. G., Yogendra N. Maurya et al. · 0 citations

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