Objectives: To estimate the absolute benefit of adding and prolonging androgen deprivation therapy (ADT) to radiation therapy (RT) for men with localized prostate cancer by integrating cancer-specific risk, other-cause mortality (OCM) risk, and relative treatment efficacy. Subjects and Methods: Individualized risks wer...
Jessica Aldous, W. Jackson, Elizabeth Chase et al.· medRxiv· 0 citations
Overtreatment of low‐risk prostate cancer (PC) undermines screening efforts. Active surveillance is preferred for low‐risk PC, but declining treatment may reflect diagnostic or treatment‐selection changes. We assessed diagnostic risk‐group trends among localized PC and low‐risk trends among radiation‐treated patients s...
S. Monda, Varshini S. Odayar, Maggie Yin et al.· Cancer· 0 citations
HMF is recommended over conventional fractionation for patients receiving EBRT across all risk groups, supported by high-quality randomized data demonstrating equivalent oncologic outcomes, toxicity, and quality of life, with shorter treatment duration that may reduce overall treatment burden.
Scott C. Morgan, A. Halthore, Angela Y. Jia et al.· Practical Radiation Oncology· 0 citations
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