R. Deo

Pathway Modeling of Genomic and Tissue-Specific Transcriptomic Architecture Identifies Personalized Mechanisms of Atrial Fibrillation Risk

A pathway-level multi-omics representation learning framework that converts individual genetic profiles into interpretable biological features by integrating GWAS-derived pathway burden scores with tissue-specific transcriptomic pathway signals is developed, providing a framework for interpretable genomic stratificatio...