Prediabetes is a clinically relevant cardiometabolic state and its role as an independent CV therapeutic target remains uncertain, but future trials should address phenotype-specific risk stratification and evaluate contemporary cardiometabolic therapies in appropriately powered populations.
F. Biondi, S. Ghelardoni, E. Monti et al.· Atherosclerosis· 0 citations
The expanding use of transcatheter aortic valve implantation (TAVI) in low-risk patients with severe aortic stenosis, including populations underrepresented in pivotal trials and often beyond established guideline recommendations, makes extended follow-up from TAVI versus surgical aortic valve replacement (SAVR) trials...
M. Sousa Uva, Milan Milojevic, M. Marín-Cuartas et al.· Annals of Thoracic Surgery· 0 citations
The rationale and design of a genetic substudy aimed at clarifying the prognostic relevance of CYP2C19 genotype in AF patients undergoing PCI and informing the design of future genotype-guided antithrombotic trials are described.
S. Chiusolo, A. Verburg, C. Morizzo et al.· Bleeding Thrombosis and Vasc...· 0 citations
Advanced diagnostic testing was associated with a higher likelihood of a determined etiologic diagnosis in MINOCA, despite marked international variability in its use; however, this association is partly definitional, as advanced testing directly contributes to diagnostic ascertainment for several etiologic categories.
D. Morrone, M. Alberti, J. Cravo et al.· European Journal of Preventi...· 0 citations
Among CCS patients, LMCAD/LMCAD-equivalent can be excluded with high negative predictive value through a model based on clinical and EST parameters, allowing initial non-invasive management of most patients able to exercise.
M. D. De Carlo, M. A. Malanima, L. Baglietto et al.· European Heart Journal· 0 citations
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