Author

R. D. Mullins

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Open access Sep 2026

De novo pan-rhodamine binders for fluorescence microscopy from mammalian cells to extremophiles.

Fluorescent imaging in live cells is a cornerstone of life sciences. While natural fluorescent proteins have been engineered to enhance individual features, no existing tag combines ideal properties into a single system: high brightness, reversible binding, compact size, and stability across diverse conditions. Here, w...

Yu-Da Chen, Klaus Yserentant, Kibeom Hong et al. · Cell · 0 citations

Open access Aug 2026

Actin filament assembly driven by distributive polymerases clustered on membrane surfaces.

It is concluded that surface-mediated polymerization can outpace solution-mediated elongation, even at high actin concentrations (>100 μM); the finite time required for profilin dissociation decreases the advantage conferred by surface-associated polymerases, but only in the absence of force.

R. D. Mullins, Jane Kondev, Kristen Skruber · Biophysical Journal · 0 citations