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Author

R. Crescitelli

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Open access Jul 2026

Extracellular vesicle secretome from mesenchymal stromal cells prevents post-ischemic heart failure by targeting cardiac fibrosis.

A clinically approved PDGFRβ-targeted PET-imaging platform for longitudinal assessment of fibrotic activity in STEMI patients and preliminary observations suggest that myofibroblast activation persists for up to 2 months after STEMI in selected patients establish a translational therapeutic-diagnostic framework for ind...

Karl-Henrik Grinnemo, Ken Braesch-Andersen, Johan O. Wedin et al. · 1 citation
Open access Jul 2026

STING-dependent peripheral inflammaging drives neurodegeneration via extracellular vesicles.

PD represents an accelerated aging disorder driven by STING-dependent inflammation, and LRRK2GoF is identified as a key driver of accelerated aging and systemic inflammaging through DNA-containing EVs, highlighting potential therapeutic targets to counteract inflammaging and neurodegeneration.

M. Öberg, Caitlyn Myers, Najmeh Saffarzadeh et al. · 1 citation

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