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Open access Sep 2026

Emergence of short-lived meningococci causing focal epidemics can be associated with gene transfer from carriage-associated Neisseria

In March 2026, an unusually large outbreak of invasive meningococcal disease (IMD) in Kent, UK, was linked to attendance at one nightclub over a single weekend. The outbreak organism was a Neisseria meningitidis variant belonging to the longstanding hyperinvasive genotype, cc41/44. Using genome analysis of six isolates...

C. Rodrigues, J. Lucidarme, R. Exley et al. · 0 citations
Review Open access Sep 2026

Prevalence and risk factors for oropharyngeal carriage of Neisseria meningitidis and circulating genogroups in eastern and southwestern Ethiopia

Neisseria meningitidis is a leading cause of meningitis epidemics in the African meningitis belt. Where invasive meningococcal disease surveillance is limited, carriage studies can identify circulating sero/genogroups to inform vaccine policies. We aimed to estimate the prevalence, identify the circulating genogro...

L. Regassa, N. Assefa, C. Trotter et al. · 0 citations
Open access Sep 2026

Hypervirulent serogroup W meningococcal strain belonging to the ST-11 clonal complex is associated with higher case fatality rates: nationwide cohort study of invasive meningococcal disease caused by serogroup W in England from 2010-2019.

BACKGROUND In 2009, England experienced an increase in serogroup W (MenW) invasive meningococcal disease (IMD) caused by the hypervirulent ST-11 clonal complex (MenW:cc11) South American strain sublineage. The 'original UK strain' that emerged in 2009 evolved into the '2013 strain' in 2013 resulting in further increase...

C. Isitt, Helen Campbell, J. Lucidarme et al. · 0 citations

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