Author

R. Benedetti

3 papers indexed here

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Open access Aug 2026

FCGR3A Polymorphism Controls B-Cell Repopulation Kinetics in People With Multiple Sclerosis Treated With Ocrelizumab

Background and Objectives Fc gamma receptor 3A (FCGR3A) V158F polymorphism has been shown to modify the response to anti-CD20 therapy across several autoimmune diseases. Ocrelizumab (OCR), an anti-CD20 agent, suppresses inflammatory activity in multiple sclerosis (MS), yet whether FCGR3A V158F polymorphism affects its...

G. Abbadessa, U. Chianese, Claudia Russo et al. · Neurology(R) neuroimmunology... · 0 citations

#machine learning Preprint Sep 2026

Multi-center Medical Data Mining with FL-Net - A One-stop Shop for Federated Learning

Federated learning enables collaborative training without sharing patient-level data, but most studies remain simulations. Based on five requirements derived from the literature, we analyzed 14 FL frameworks and found that none fully satisfied these requirements. We present FL-Net, a novel federated clinical research f...

Simon Süwer, Juliane Klemm, E. Acitelli et al. · 0 citations

Review Open access Jul 2026

Interplay Between DNA and RNA Methylation Shapes Cancer Cell Plasticity.

Cellular plasticity refers to the ability of healthy cells to shift between phenotypic states and modify their characteristics to maintain tissue homeostasis and integrity. In the tumor context, cancer stem cells (CSCs) exploit this flexibility to withstand stress, facilitate tumor dissemination, and evade therapeutic...

Guglielmo Bove, U. Chianese, Antonio Beato et al. · Seminars in Cancer Biology · 0 citations