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Gene regulation in human metabolic homeostasis: PPARg perturbation and Cold exposure as models of intrinsic and extrinsic metabolic regulation
Metabolism refers to the integrated network of all biochemical reactions that sustains organismal function. In humans and other mammals, systemic metabolic homeostasis arises from the interplay of multiple organs that exchange circulating metabolites. Two major human metabolic organs are adipose tissue (AT) and the ske...