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Open access Oct 2026

Sputum and oral microbiota profiles are associated with long COVID severity and phenotype post-hospitalisation: a UK multicentre, prospective cohort study.

BACKGROUND Acute COVID-19 alters the airway microbiota. Whether these changes persist post-COVID-19 and contribute to long COVID is unknown. We aimed to describe the microbiota by long COVID severity and subtype, and identify links with inflammation. METHODS Adults were prospectively recruited to the longitudinal UK...

Daniela Alferes de Lima Headley, H. Richardson, C. Hennayake et al. · 0 citations
Open access Sep 2026

Effectiveness of nebulised 7% saline versus oral carbocisteine in patients with COPD and self-reported difficulty in expectoration: a randomised controlled trial (MUCACT)

This was an open, pragmatic, UK, multicentre and parallel randomised controlled trial in participants with COPD and self-reported difficulty in expectorating. Participants were randomised to receive either nebulised 7% saline plus the active cycle breathing technique (ACBT) twice daily or carbocisteine plus...

A. Hill, S. Tuck, A. Sheikh et al. · 0 citations

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