Macrophage polarization regulated by the βTrCP-NF-κB inflammatory signaling pathway is required for valproic acid’s dual role in breast tumor radiosensitivity and normal tissue radioprotection
Radiotherapy (RT) is a widely used treatment modality for breast cancer, but its broad application is limited by the risk of adverse effects, such as the potential for the tumor to develop resistance to RT. Identifying strategies that enhance RT efficacy while minimizing adverse effects is of significant clinical impor...