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Author

Quan-Kun Lv

2 papers indexed here

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Sep 2026

A Paired Tumor Organoid-Stroma Biobank Reveals PLAU⁺ Fibroblasts as Drivers of Chemoresistance in Lung Adenocarcinoma.

Chemotherapy is a standard treatment for lung adenocarcinoma (LUAD), yet the efficacy is often limited, highlighting the need to elucidate and the underlying mechanisms of chemoresistance. Given the important role of the tumor microenvironment in LUAD progression, we established a biobank of patient-derived LUAD organo...

Si-Qi Li, Ze Zhang, Quan-Kun Lv et al. · 0 citations
Open access Oct 2026

Assessing the consistency of a prognostic transition to persistent critical illness across two U.S. ICU databases: a daily risk-set analysis.

OBJECTIVE To test whether an apparent prognostic transition to persistent critical illness persists after daily clinical-state updating. DESIGN Retrospective daily risk-set analysis using multicenter eICU discovery, single-health-system MIMIC-IV concept replication, cluster-resampled simultaneous inference, and post-...

Guo-Xin Wu, Quan-Kun Lv, Ying-Er Ye et al. · 0 citations

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