Sustained Humoral Activation through self-amplifying mRNA Vaccination Enhances Longitudinal Antibody Function in a Phase III Trial 2305471
The development and deployment of mRNA vaccines during the COVID-19 pandemic was a landmark achievement in modern medicine and ushered in a new age of vaccine innovation. The vaccines strongly elicited both neutralizing and non-neutralizing antibody responses against the viral Spike protein, but these waned over...