Roles of cerebrospinal fluid metabolites in neuromyelitis optica spectrum disorder: Insights from Mendelian randomization
The roles of several CSF metabolites in NMOSD are elucidated, with specific glycerophosphocholine species showing risk associations in AQP4-IgG positive and AQP4-IgG negative subtypes, while ascorbate and N-acetylhexosamines demonstrate protective effects across both subtypes, thereby providing valuable insights.