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Qiu-Yi Li

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Open access Oct 2026

Carbon-A: Unified Genome Annotation across Eukaryotic Diversity

Structural genome annotation remains a bottleneck in eukaryotic genomics as conventional methods depend on external evidence that is unevenly available across the tree of life, and existing ab initio predictors are typically specialized for particular taxonomic groups. We introduce Carbon-Annotator (Carbon-A), a 1.2-bi...

Georgia Channing, Zheng Shi, Xiao-Xi Zhang et al. · 0 citations
Open access Sep 2026

scRep: A Latent-Space Self-Distilled Foundation Model for Single-Cell Representation Learning

Single-cell foundation models have shown strong potential for learning transferable representations from large-scale transcriptomic data. However, many existing approaches rely on reconstructing masked gene expression values, creating a potential mismatch between observation-space reconstruction and the goal of learnin...

Sheng-Jie Wang, Zong-Yong Hu, Yunlong Bie et al. · 0 citations

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