Author

Qiuwen He

2 papers indexed here

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Open access Oct 2026

Metabolite-Driven Immunosuppression in High-Risk NSCLC — with Anti-Tumor Immunity Shaped by Probiotic Strategy, Donor Origin, and Conserved Microbial Mediators

Elevated serum cytokeratin 19 fragment (CYFRA 21-1) in non-small cell lung cancer (NSCLC) links to immunosuppression, but whether live gut bacteria or their metabolites mediate this effect remains unclear. Using stratified fecal microbiota transplantation in a Lewis lung carcinoma model, we demonstrate that cell-fr...

Cui-Jiao Feng, Guang-Qi Gao, Qiu-Wen He et al. · Food Science and Human Welln... · 0 citations

Open access Sep 2026

Bifidobacterium animalis subsp. lactis V9 overcomes CYFRA 21-1–linked immunochemotherapy resistance in NSCLC via microbial metabolites

Gut dysbiosis drives therapeutic resistance, yet the relationships among typical tumor markers, gut microbiota, and treatment efficacy remain poorly defined. Here, elevated serum CYFRA 21-1 in advanced non–small cell lung cancer (NSCLC) correlates with gut dysbiosis, including Bifidobacterium animalis depletion and red...

Cui-Jiao Feng, Guang-Qi Gao, Qiuwen He et al. · Science Advances · 0 citations