Author

Qiu-Shi Lin

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Open access Oct 2026

A Dual-Marker DNA Methylation Assay Enables High-Sensitivity Detection of Malignant Effusions Across Cancer Types

Simple Summary Distinguishing malignant from benign pleural and peritoneal effusions is essential for cancer diagnosis and treatment, but routine cytology often fails to detect malignant cells. We evaluated a DNA methylation test based on two cancer-related genes, SHOX2 and RASSF1A, in 696 patients with pleural or peri...

Ting Wang, Ting Liang, Matthew Kafarski et al. · Cancers · 0 citations

Review Open access Aug 2026

Clinical value of combined SHOX2 and RASSF1A methylation in lung cancer diagnosis across tissue and liquid biopsy samples: a systematic review and meta-analysis

Lung cancer remains the leading cause of cancer-related mortality worldwide, with poor prognosis in advanced stage diseases. Although early diagnosis has the potential to improve patient outcomes, current diagnostic methods remain suboptimal, highlighting the need for accurate molecular biomarkers. We systematically re...

Ting Wang, Jian-Guo Zhang, Jia-Yang Wang et al. · Oncology Reviews · 0 citations