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Qiu-Ran Ji

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Oct 2026

The deubiquitinase OTUD1 aggravated dopaminergic neurodegeneration in Parkinson's disease model by promoting the degradation of Parkin.

Parkin plays a pivotal role in the pathogenesis of Parkinson's disease (PD). Deubiquitinating enzymes (DUBs), which reverse Parkin ubiquitination, are critical for maintaining mitochondrial homeostasis. Although ovarian tumor protease deubiquitinase 1 (OTUD1) participates in various biological processes, its specific f...

Meng-Ting Wu, Teng-Fei Liu, Run-Zhe Zong et al. · 0 citations

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