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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Qiongzhu Dong

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2 papers indexed here

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Open access Oct 2026

Disruption of ACTG1 potentiates anti-TIM-3 immunotherapy by reprogramming the immunosuppressive microenvironment via the CSF3/CSF3R axis in pancreatic cancer

Background The limited immune infiltration observed in pancreatic ductal adenocarcinoma (PDAC) is a major factor contributing to immunotherapy resistance and the consistently poor prognosis. Hence, identifying novel therapeutic targets and developing effective combination strategies to overcome immunotherapy resistance...

Le Zhu, Yu Guo, Xin-Xin Ling et al. · 0 citations
Open access Jul 2026

LSD1-GLS2 axis drives subtype-specific chemoresistance in pancreatic cancer through glutaminolysis reprogramming

It is shown that LSD1 knockdown has opposing, subtype-specific effects on chemotherapeutic responses: it sensitized RSK-subtype cells to chemotherapy but induced resistance in KRAS-subtype cells, revealing mitochondrial dysfunction and defective mitophagy as hallmarks distinguishing KRAS- from RSK-subtype PDAC.

Zhe-Fang Wang, Qiu Huang, Jian-Gang Zhao et al. · 1 citation

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