Gene-Specific Rewiring of Type I Interferon Responses by Staphylococcus aureus 2329926
The findings suggest that S. aureus alters activation of the canonical type I IFN-mediated Jak-STAT pathway through suppression of STAT1 activation and altering chromatin remodeling and may alter the host response to this pathogen in a context-dependent manner and contribute to difficulty in clearing S. aureus infection.