In vivo and in vitro experiments demonstrated that HDG alleviated renal injury in ADR-induced FSGS in mice and attenuated TGF-β1-induced damage in MPC5 cells, which support HDG as a promising therapeutic candidate for FSGS treatment.
The present review systematically outlines the clinical manifestations, core pathogenic mechanisms and emerging therapeutic strategies for CKD‑associated encephalopathy, and the targeted interventions on the gut‑kidney‑brain axis.
Nanling Zeng, Ling Jiang, Yang Zhang et al.· Molecular Medicine Reports· 0 citations
This review systematically synthesizes advances in the pivotal, context-dependent roles of BTG2 in non-tumor pathologies, including fibrotic, neurological, cardiovascular, inflammatory, metabolic and other systemic diseases.
Shu-Ling Li, Xiao-Mei Liu, Zheng Zhang et al.· International Journal of Mol...· 0 citations
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