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Qinglin Gan

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Aug 2026

Honokiol Targets Cyclophilin D and Blocks Mitochondrial DNA Release to Inhibit Microglial NLRP3 Inflammasome Activation and Alleviate Neurodegeneration in Parkinson's Disease Models.

Parkinson's disease (PD) is linked to neuroinflammation, and the current focus of treating PD is to alleviate its pathological symptoms rather than neuroprotection. Honokiol (HNK), an active component of Magnolia officinalis, has been reported to be neuroprotective in PD models, but its mechanism remains unclear. In th...

Qinglin Gan, Yingtong Xian, Ting Zhou et al. · 0 citations

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