Case report
Open access
Sep 2026
Dynamic clonal evolution of multiple bypass resistance mechanisms in EGFR-mutant lung adenocarcinoma: a case report
The case of a 62-year-old male with stage IIB poorly differentiated lung adenocarcinoma harboring an EGFR L858R-mutant lung adenocarcinoma can undergo stepwise clonal evolution of multiple bypass resistance mechanisms under aumolertinib selective pressure.
Qing-Yun Zhang, Xiao-Yan Yin
· Frontiers in Oncology · 0 citations