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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Qing-Yue Li

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Open access Sep 2026

GPCR antagonism via rewiring of receptor trafficking and degradation

A novel strategy for functional GPCR antagonism via bispecific antibody-mediated endocytosis and lysosomal degradation is reported via bispecific antibody-mediated endocytosis and lysosomal degradation, establishing induced endocytosis and rewiring protein trafficking as a new paradigm for therapeutic GPCR modulation.

Kaitlin Rhee, L. Shue, Akimasa Adachi et al. · 1 citation

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