Sep 2026
CCND1 Mitigates Ischemia-Induced Pathological Cardiac Remodeling by Promoting Cardiac Monocyte-Derived Macrophage Transition to a Reparative Phenotype.
The findings identify the CCND1-PDK4 axis as a key regulator of macrophage functional reprogramming toward a reparative phenotype after MI, highlighting it as a potential therapeutic target in postinfarction remodeling.
Chu-Han Wang, Hui-An Han, Kai-Lai Li et al.
· Circulation · 0 citations