Author

Qing Xu

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#protein folding Review Oct 2026

Harnessing Biotechnology for the Development of Brazzein as a Next-Generation Sweetener

Sugar reduction has emerged as a major direction in the food industry, increasing the need to reduce sucrose while maintaining desirable sweetness quality. Brazzein, a high-intensity sweet protein, has attracted considerable interest. Depending on the sucrose reference concentration, its sweetness potency ranges from...

Jia-Yi Wan, Yuan-Fei Wang, Dong-Dong Yang et al. · Journal of Agricultural and... · 0 citations

Review Oct 2026

Genome-scale metabolic models enable predictive strain and process design for sustainable biomanufacturing.

Genome-scale metabolic models (GEMs) have emerged as powerful tools for optimizing microbial fermentation. This review traces the application of GEMs from model reconstruction through to industrial implementation. Automated reconstruction tools including CarveMe, ModelSEED, and RAVEN are discussed alongside quality-con...

Shuai-Shuai Xu, Ji Ding, Shu-Yi Chen et al. · Biotechnology Advances · 0 citations

Aug 2026

Rational Engineering of Chitosanase for Producing Higher-Degree-of-Polymerization Chitooligosaccharides and Evaluating Their Antibacterial Properties.

A rational design strategy was developed to increase the DP of COS by introducing three negatively charged mutations into chitosanase Csn168 (a chitosanase from Bacillus subtilis 168) and the resulting high-DP COS exhibited potent antibacterial activity against Staphylococcus aureus.

Zhangyi Chen, Jiawei Luo, Chenglin Wu et al. · Journal of Agricultural and... · 1 citation