The uric acid-to-homocysteine ratio as a prognostic marker for all-cause and cardiovascular mortality: A national population-based study
The homocysteine (Hcy) paradox, the failure of Hcy-lowering therapies to consistently reduce cardiovascular events, remains a major challenge in metabolic medicine. We hypothesize that adenosine (Ado), a stoichiometric byproduct of Hcy production with vascular protective effects, may be relevant to this paradox....