Episomal plasmids are widely used in yeast metabolic engineering for their flexibility and high transformation efficiency. However, their application in Yarrowia lipolytica is often limited by low copy number and insufficient genetic stability. In this study, a robust episomal plasmid that balanced genetic stability an...
These findings identify POA as an active metabolic modulator, not merely a passive structural lipid, pointing to a non-transgenic nutritional strategy whose industrial value now requires validation under high-gravity, pilot-scale, and serial-repatching conditions.
This work provides the first evidence of GldL glycosylation and establishes its critical role in T9SS function, and offers a novel perspective for elucidating cellulose degradation in C. hutchinsonii.
Wenxia Song, Zizhe An, Shu-Hang Zhang et al.· International Journal of Bio...· 0 citations
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