Author

Qing Li

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Review Open access Sep 2026

HIV-driven tumor ecosystem: from chronic immune dysfunction to cancer evolution

This review comprehensively examines the components and dynamic changes within the tumor ecosystem of HIV-infected patients, focusing on how HIV-mediated CD4+ T-cell depletion, immune checkpoint dysregulation, chronic antigenic stimulation, and direct effects of viral proteins such as Tat and Nef facilitate tumor immun...

Guang Zhou, Juan-Yan Liao, Hao-Lin Tang et al. · Frontiers in Microbiology · 0 citations

Jul 2026

Single-Cell Analysis of Residual Esophageal Squamous Cell Carcinoma After Neoadjuvant Immunochemotherapy Reveals TFAM-Mediated Immunoregulation in Dendritic Cells.

The TME in residual ESCC after nICT is characterized and revealed an association between elevated TFAM expression in DCs and poor responsiveness to nICT, indicating the critical role of TFAM deficiency in DCs in activating anti-tumor immunity.

Linyan Chen, Tang Feng, Jian-Feng Zhou et al. · Cancer Research · 1 citation