Open access
Sep 2026
γ-Glutamylcysteine alleviates hypertension and vascular remodeling in SHR by suppressing oxidative stress through Keap1 S-glutathionylation
Abstract Objectives Pathological arterial remodeling heavily depends on the aberrant proliferation and migration of vascular smooth muscle cells (VSMCs). This study explores how γ-Glutamylcysteine (γ-GC) regulates VSMC signaling to mitigate hypertensive structural damage. Methods Spontaneously hypertensive rats (SHR) a...
Jian-Zhen Lei, Yue-Ru Kong, Chao Ye et al.
· Redox Report · 0 citations