Author

Qing-Jie Lv

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Open access Aug 2026

Benchmarking of pathology foundation models for assessing HER2 amplification and CEP17 polysomy in breast cancer

Accurate assessment of Human Epidermal Growth Factor Receptor 2 (HER2) amplification and Chromosome 17 (CEP17) copy number is critical for breast cancer treatment, yet diagnostically equivocal (IHC 2+) cases remain a clinical bottleneck. This study systematically benchmarks 14 feature encoders, including 12 Pathology...

Qing-Jie Lv, Xin Yu, Tao Wang et al. · npj Breast Cancer · 0 citations

Open access Oct 2026

Knowledge-guided Multimodal Learning for Interpretable Prediction of Pathological Complete Response and Survival in Breast Cancer.

PURPOSE Pretreatment estimation of pathological complete response (pCR) to neoadjuvant chemotherapy may support risk stratification and future response-adapted clinical studies in breast cancer. However, existing deep learning approaches often rely on "black-box" visual pattern recognition, suffering from poor interpre...

Wen-Chuan Zhang, Shu-Wan Zhang, Ya-Ni Wei et al. · Laboratory investigation; a... · 0 citations