Author

Qing-Hua Peng

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Review Open access Sep 2026

Nrf2/HO-1 signaling in retinal neurodegenerative diseases: redox homeostasis, cytoprotection, and therapeutic perspectives

This review critically synthesizes the cytoprotective roles, evidence boundaries, translational challenges, and future directions of Nrf2/HO-1 signaling in RNDs, organized around retinal cell types, redox homeostasis-related injury mechanisms, disease-specific evidence, and intervention strategies.

Yu Tang, Xiao-Lei Yao, Qing-Hua Peng · Frontiers in Medicine · 0 citations

Open access Aug 2026

Dietary Lycium barbarum Polysaccharides Support Retinal Redox Homeostasis Through Gut Microbiota–Associated Metabolic Modulation

The nutritional significance of LBP as a functional polysaccharide is highlighted and the concept that dietary modulation of gut microbiota–associated metabolism may contribute to maintaining retinal metabolic homeostasis is supported.

Yi-Jing Yang, Jun Peng, Dan-Yang Li et al. · Food Science & Nutrition · 0 citations

Open access Aug 2026

A Structurally Characterized Lycium barbarum Polysaccharide Protects Against Retinal Degeneration Through Nrf2 Activation and NF-κB/NLRP3 Suppression

Retinal degeneration is characterized by progressive photoreceptor loss driven by oxidative stress and chronic inflammation, yet effective mutation-independent therapeutic strategies remain limited. Lycium barbarum polysaccharides (LBPs) possess antioxidant and anti-inflammatory activities; however, the structural feat...

Yi-Jing Yang, Shu-Ting Yin, Ying Deng et al. · Antioxidants · 0 citations