Purpose
Acanthamoeba keratitis (AK) is a vision-threatening corneal infection characterized by intense inflammation and tissue damage. Although innate immunity is critical for host defense against Acanthamoeba, the pattern recognition receptors (PRRs) involved in pathogen sensing remain incompletely defined. This study...
Mycovirus infection attenuates A flavus pathogenicity and modulates host responses in FK, suggesting a potential role for viral carriage in the clinical heterogeneity of disease severity.
Zhen Cheng, Xin Luo, Qing-Quan Shi et al.· Investigative Ophthalmology...· 0 citations
DECTIN-1 was dynamically upregulated during AK and may play a potential role in mediating innate immune responses and shaping immune cell dynamics and indicated DECTIN-1 as a potential therapeutic target.
J. Pang, Zhen-Yu Wei, Yu-Heng Zhang et al.· Investigative Ophthalmology...· 0 citations
Background: Hypervirulent Klebsiella pneumoniae (K. pneumoniae) easily causes bacteremia and liver abscess, and invades the eye via blood circulation to trigger blinding endogenous endophthalmitis. Widespread multidrug resistance limits antibiotic treatment, while traditional capsular polysaccharide vaccines cannot pro...
Jia-Ying Lei, Xin-Xin Lu, Ti-Yun Han et al.· Pathogens· 0 citations
We use cookies to run the site and, with your consent, for analytics and to show ads.
See our Cookie Policy.
