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Author

Qinan Yin

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Review Open access Aug 2026

Adaptive-to-maladaptive IRE1α signaling as a driver of amyloidogenic APP processing in Alzheimer’s disease

How dynamic changes in IRE1α signaling bias contribute to amyloidogenic progression in AD is examined and whether selective modulation of adaptive versus maladaptive IRE1α outputs may offer stage-dependent therapeutic benefit is considered.

Dan-Yun Wang, Qinan Yin · 0 citations
Open access Jul 2026

Unraveling role of arginine-NO metabolism by targeting HIF-1α signaling in mediating esophageal squamous cell carcinoma

It is confirmed that ESCC exhibits significant amino acid metabolic dysregulation, with arginine related metabolic pathways being significantly enriched, and NO can serve as a potential non-invasive biomarker for distinguishing ESCC.

Kaiyuan Yao, Shunshun Zhang, Siya Tang et al. · 0 citations

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