Author

Qin Liu

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Sep 2026

ROS-xCT metabolic coupling defines an astrocyte subtype that drives glutamate excitotoxicity during Alzheimer's disease progression.

Ast.1 is defined as a pivotal driver of microenvironmental collapse in AD, unveiling a novel microglia-astrocyte-neuron pathogenic cascade mediated by the ROS-xCT metabolic hub.

Xue-Man Xie, Wen-Jing Liu, Long-Chao Chen et al. · Life Science · 0 citations