F122. SYSTEMATIC STRUCTURAL CHARACTERIZATION OF MISSENSE MUTATIONS IN SCHIZOPHRENIA RISK GENES
Background Schizophrenia (SCZ) is a highly heterogeneous psychiatric disorder in which rare missense variants are increasingly recognized as major contributors to disease risk. Recent advances in next-generation sequencing (NGS), AlphaFold-based protein structure prediction, and machine learning provide unprecedented o...
Shaolei Teng, Malcolm Anthony, Qiaobin Yao et al.
· European Neuropsychopharmaco... · 0 citations