Background Gastric cancer (GC) remains a leading cause of cancer-related mortality, with progression driven largely by the tumor microenvironment (TME). Tumor-associated macrophages (TAMs), the most abundant immune cells in the GC stroma, drive immune evasion, angiogenesis, metastasis, and chemoresistance through polar...
Xiaodong Zhuang, Qiang Yang, Liangjiu Huang et al.· Frontiers in Oncology· 0 citations
Background Osteosarcoma is the most prevalent primary malignant bone tumor in adolescents, featuring prominent intratumoral heterogeneity, early pulmonary metastasis and stagnant survival improvement for metastatic/chemoresistant patients. Altered lipid metabolism represents as a core adaptive hallmark of malignancy, w...
Xian-Fu Wei, Zhi-Peng Wang, Qiang Yang et al.· Frontiers in Immunology· 0 citations
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