#protein folding
Sep 2026
Screening strong anaerobic E. coli promoters to enhance therapeutical protein expression in tumors.
This study reports the first systematic screening of strong constitutive anaerobic promoters in the probiotic Escherichia coli Nissle 1917 (EcN), establishing a precision delivery framework for potent yet highly toxic anticancer agents, facilitating the development of bacterial biotherapeutics.
Tian-Qi Cui, Guang-Le Yu, Chan-Juan Jiang et al.
· Journal of Controlled Releas... · 0 citations