Oct 2026
Identification of Thioredoxin-Interacting Protein as an Upstream Regulator of Ferroptosis in Hyperuricemic Nephropathy.
AIM Hyperuricemic nephropathy (HN) is a major contributor to chronic kidney disease, yet current urate-lowering therapies often fail to halt tubular injury once established. While ferroptosis is known to drive renal injury in HN, the upstream molecular mechanisms remain unclear. We investigated whether thioredoxin-inte...
Yue-Mei Xi, Qiang Wang, Ya-Yan Liu et al.
· Antioxidants and Redox Signa... · 0 citations