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Open access Oct 2026

Benzo[a]pyrene and bisphenol A interact to induce combined pulmonary toxicity through an integrated transcriptomic-metabolomic network.

Widespread atmospheric pollutants such as benzo[a]pyrene (BaP) and bisphenol A (BPA) persistently coexist, yet their combined risks to the respiratory system remain largely overlooked. In this study, C57BL/6J mouse and A549 cell models were employed to investigate the combined pulmonary toxicity induced by BaP and BPA,...

Guang-Chao Yang, Xiao-Yan Jiang, Liu-Hong Wang et al. · 0 citations
Sep 2026

Ganoderma lucidum spore oil ameliorates high-fat-diet-induced hepatic lipid metabolism disorder by modulation of the gut microbiota.

BACKGROUND Obesity is a major global public health challenge. A high-fat diet (HFD) is a key contributing factor, closely associated with gut microbiota dysbiosis. Although immunomodulatory effects of Ganoderma lucidum spore oil (GLSO) have been reported, its role in lipid metabolism disorders and its interaction with...

Jia-Ning Zhang, Yuan-Lan Yang, Xin-Yi Zhou et al. · 0 citations

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