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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Qian Wang

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Open access Aug 2026

Sec61β Deficiency Disrupts Drosophila Oogenesis Through UPR-Mediated Defects in Germ Cell Proliferation and Differentiation

It is found that knockdown of Sec61β in either germ cells or somatic cells of ovaries causes complete female sterility, with a small size of ovaries from larval to adult stages, significant reduction in germ cell numbers beginning in the late third-instar larval stage and a complete absence of germ cells in pupal and adult ovaries.

Zhi-Xian Cao, Xiao-Min Xiao, Yi-Ming Ji et al. · 0 citations

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