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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Qian-Quan Sun

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Open access Aug 2026

Transcriptome-Inspired Spiking Simulations Uncover Human-Specific Prefrontal Dynamics and Provide a Mechanistic Platform for Species-Appropriate Disease Modeling

Whole-brain transcriptomic atlases are now widely available, yet computational neural models are almost exclusively parameterized from rodent data and used to infer human brain function, an extrapolation whose cost remains unquantified. To address this, we constructed a biophysically detailed, conductance-based Hodgkin...

Qian-Quan Sun, Yihan Wang, Chunzhao Zhang · 0 citations

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