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Qian-Qian Lou

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Open access Aug 2026

H2BK5ac is required for the establishment of inflammatory potential in mouse embryonic stem cells following differentiation.

Embryonic stem cells (ESCs) are refractory to inflammatory stimuli but acquire inflammatory competence upon differentiation, yet the underlying mechanisms remain unclear. Here, we report that H2BK5ac regulates the acquisition of inflammatory potential in mouse ESCs during differentiation. H2BK5ac levels increased at th...

Yan Xi, Shuai Pei, Qian-Qian Lou et al. · 0 citations

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