EIF1 coordinates transcriptomic and splicing networks associated with cell cycle dysregulation in diabetic retinopathy
Purpose EIF1, an RNA-binding protein implicated in multiple diseases, remains poorly characterized in diabetic retinopathy (DR). This study therefore investigated EIF1 expression and function in an in vitro model of DR pathogenesis. Methods Human retinal pigment epithelial cells (ARPE-19) were exposed to 50 mM glucose...